I also bought my wife a Charter revolver in .38 spl. +P ammunition is loaded at higher pressures for higher velocities where "non-+P ammo is loaded to lower or standard pressures for that particular cartridge. This extra pressure increases stress on the frame of the gun which may lead to some type of decrease in the integrity of it. I don't know if it would be safe or not, it might just be a liability issue for the manufacturer, however I personally and don't take that chance on our Charter. I'd try to take it back or try to sell it so anyone with a .38 or .357 revolver.